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博导介绍

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黄晓华(外聘)

黄晓华   性别:女 出生日期:1958年10月1日 职称:教授 联系电话:025-85891651(办公) 电子邮件:huangxiao@njnu.edu.cn

【学术简介】

〖学习经历〗:1978-1982于安徽师范大学化学系学习;1985-1987在北京大学化学系研究生课程学习。〖研究经历〗:1991 -1992在北京大学作高级访问学者;1994为硕士生导师;2003为博士生导师。〖学术及社会兼职〗:2006年兼聘国家发改委稀土专家;2008年兼聘江苏省高级人民法院知识产权厅专家及其人民陪审员;2009年兼聘稀土化学农医专业委员会副主任等。

【主讲课程】

博士研究生:

硕士研究生:

本 科 生:

【指导硕、博士生研究方向】

博士研究生:从事化学与生物学交叉研究领域,主要研究方向为生物无机化学,即将生物物理化学研究手段、细胞化学方法与细胞生物学技术优化组合,研究稀土元素、重金属离子、医用纳米材料对细胞及其生物酶分子的结构、功能及其微观化学过程的影响。

硕士研究生:从事化学与生物学交叉研究领域,主要研究方向为生物无机化学,即将生物物理化学研究手段、细胞化学方法与细胞生物学技术优化组合,研究稀土元素、重金属离子、医用纳米材料对细胞及其生物酶分子的结构、功能及其微观化学过程的影响。

【研究领域】

从事化学与生物学交叉研究领域,主要研究方向为生物无机化学,即将生物物理化学研究手段、细胞化学方法与细胞生物学技术优化组合,研究稀土元素、重金属离子、医用纳米材料对细胞及其生物酶分子的结构、功能及其微观化学过程的影响。

【主要论著】

(1) Na Jiang, Lihong Wang, Chunlei Du, Xiaolan Ding, Xiaohua Huang*. The formation of a new horseradish peroxidase binding rare earth. Environ. Chem. Lett.2011.9(2):191-196.

(2) Wenbo Zhao, Guohui Zhang, Lancao Jiang, Tianhong Lu, Xiaohua Huang∗, Jian Shen∗. Novel polyurethane ionomer nanoparticles displayed a good biosensor effection. Colloids and Surfaces B: Biointerfaces.2011, 88 : 78–84.

(3) Guohui Zhang,Yi Fang, Jian Shen, Chun Mao∗, Xiaohua Huang∗. Cytocompatible Performance of Thermosensitive Poly(N-Isopropylacrylamide) Nanoparticles. Journal of Biomaterials Science. 2011, 1–10.

(4) Guohui Zhang, Ningbo Yang, Yalong Ni, Jian Shen, Wenbo Zhao∗, Xiaohua Huanga∗. A H2O2 electrochemical biosensor based on biocompatible PNIPAM-g-P(NIPAM-co-St) nanoparticles and multi-walled carbon nanotubes modi?ed glass carbon electrode. Sensors and Actuators B. 2011,158 : 130–137.

(5) Zhenping Chen, Dongmei Sun∗, Yiming Zhou, Jiayue Zhao, Tianhong Lu, Xiaohua Huang∗,Chenxin Cai, Jian Shen. Nano polyurethane-assisted ultrasensitive biodetection of H2O2 over immobilized Microperoxidase-11.Biosensors and Bioelectronics.2011,29:53-59.

(6) Wang L, Jiang N, Zhao B, Li X, Lu T, Huang X∗. Structural basis for the decrease in the outward potassium channel current induced by lanthanum. Journal of Biological Inorganic Chemistry. 2010,15(7):989-993.

(7) Wang L, Zhou Q, Lu T, Ding X, Huang X*. Molecular and cellular mechanism of the effect of La(III) on horseradish peroxidase. Journal of Biological Inorganic Chemistry. 2010, 15(7):1063-1069.

(8) Lihong Wang, Aihua Lu, Tianhong Lu, Xianlan Ding, Xiaohua Huang*. Interaction between lanthanum ion and horseradish peroxidase in vitro. Biochimie. 2010,15(7):989-993.

(9) Wang LH, Zhou Q, Zhao B, Huang XH* .Toxic effect of heavy metal terbium ion on cell membrane in horseradish. Chemosphere. 2010,80:28-34.

(10) Wang LH, Zhou Q*, Huang XH* Effects of heavy metal terbium on contents of cytosolic nutrient elements in horseradish cell Ecotoxicology and Environmental Safety. 2010,73:1012-1017.

(11) Guo SF, Wang LH, Lu TH, Ding XL, Huang XH∗. Direct electrochemistry and electrocatalysis of complex of horseradish peroxidase and La (III) at nano-gold colloid/cysteine/gold. Electrode Journal of Electroanalytical Chemistry. 2010, 644(1):80-84.

(12) Wenru Wu,Yuzhi Rong,Bo Zhao,Peipei Sun*,Xiao hua Huang* The study on the interaction between Tb(III) and ligand in Tb–acetylsalicylic acid complex and ?uorescence mechanism. Journal of Luminescence. 2010,130:92-95.

(13) Guo SF, Wang LH, Lu AH, Lu TH, Ding XL, Huang XH∗ Inhibition mechanism of lanthanum ion on the activity of horseradish peroxidase in vitro. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2010,75(2): 936-941

(14) Xiaohua Huang, Qing Zhou, Tianhong Lu,Shaofen Guo. Design and preparation of plant growth regulator of rare earth element-amino acid-vitamine, 2009, United States Patent(EFSID;4978659;PCT/CN07/01912).

(15) Mao, C., Jiang, L.C., Luo, W.P., Liu, H. K., Bao, J. C., Huang, X. H*., Shen, J*. Novel Blood-Compatible Polyurethane Ionomer Nanoparticles. Macromolecules. 2009, 42 (23): 9366–9368..

(16) Lihong Wang, Qing Zhou, Xiaohua Huang*. Photosynthetic responses to heavy metal terbium stress in horseradish leaves. Chemosphere. 2009, 77:1019-1025.

(17) Shaofen Guo, Lihong Wang, Aihua Lu , Tianhong Lu , Xiaolan Ding, Xiaohua Huanga*.Inhibition mechanism of lanthanum ion on the activity of horseradish peroxidase in vitro. Spectrochimica Acta Part A. 2009, SAA-7462.

(18) Wang, L.H., Huang, X.H.*, Zhou, Q.* Effects of Rare Earth Elements on the Distribution of Mineral Elements and Heavy Metals in Horseradish. Chemosphere. 2008,73(3): 314-319.

(19) Shaofen Guo, Xiaolan Ding, Tianhong Lu, Qing Zhou, Xiaohua Huang*. Inhibition Mechanism of Tb(III) on Horseradish Peroxidase Activity in vitro Chemistry & Biodiversity. 2008, 5: 2050-2059.

(20) Shaofen Guo, Qing Zhou, Tianhong Lu, Xiaolan Ding, Xiaohua Huang*. One of the Possible Mechanism for the Inhibition Effect of Tb(III) on Peroxidase Activity in Horseradish (Armoracia rusticana)Treated with Tb(III). Journal of Bioogical Inorganic Chemistry. 2008, 13:587-597.

(21) Yaxin Ye, Lihong Wang, Xiaohua Huang*, Tianhong Lu, Xiaolan Ding, Qing Zhou. Subcellular Location of Horseradish Peroxidase in Horseradish Leave Treated with La(III), Ce(III) and Tb(III). Ecotoxicology and Environmental Safety. 2008, 71:677-684.

(22) Liu, H.K. *, Huang, X.H.*, Lu, T.H., Wang, X.J., Sun, W.Y., Kang, B.S. Discrete and Infinite 1d, 2d/3d Cage Frameworks with Inclusion of Anionic Species and Anion-Exchange Reactions of Ag3l2 Type Receptor with Tetrahedral and Octahedral Anions. Dalton Transactions. 2008, (24): 3178-3188.

(23) Shaofen Guo, Xiaohua Huang*, Tianhong Lu ,Xiaolan Ding, Qing Zhou. Spectroscopic studies of interactions involving horseradish peroxidase and Tb3+. Spectrochimica Acta Part A. 2008, 70: 818-823.

(24) Hui Zhou, Tianhong Lu, Hongxia Shi, Zhihui Dai, Xiaohua Huang*. Direct electrochemistry and electrocatalysis of catalase immobilized on carbon nanotubes modified glassy carbon electrode and its appilication. Journal of Electroanalytic Chemistry. 2008, 612: 173-178.

(25) Xiaoyun Guo, Mingqing Chen, Tianhong Lu, Xiaohua huang*. Effect of Tb(III) on the properties of P(NIPAM-co-St) copolymer microsphere. Journal of Polymer Research.2008, 15: 141-145.

(26) Xiaoshan Guo, Qing Zhou, Tianhong Lu, Min Fang, and Xiaohua Huang*. Distribution and translocation of 141Ce(III) in horseradish. Annals of Botany. 2007, 100:1459-1465.

(27) Guo, S.F., Zhou, Q., Lu, T.H., Ding, X.L., Huang, X.H.* Inhibition Effect of Tb(III) on Horseradish Peroxidase Activity. Journal of Biological Inorganic Chemistry. 2007,12, (S1): S203.

(28) Shaofen Guo, Qing Zhou, Tianhong Lu, Xiaolan Ding, Xiaohua Huang*. Interaction between La3+ and MP-11 in the physiological solution. Electrochimica Acta. 2007,52: 2032-2038.

(29) Xiaohua Huang *, Shaofen Guo, Qing Zhou, Tianhong Lu, Xiaolan Ding. Effect of La3+ on structure and electrochemical reaction of microperoxidase-11 in imitated physiological solution. Journal of Electroanalytic Chemistry. 2007, 600: 227–235.

(30) Weiqing Yin, Mingqing Chen, Tianhong Lu, Mitsuru Akashi, Xiaohua Huang*. Properties of complex of Tb(III) and poly(N-isopropylacrylamide)-g-poly(N-isopropylacrylamide-co-styrene) core-shell nanoparticles. Journal of Alloys and Compounds. 2007, 432: L18–L21.

【科研项目】

(1)江苏省自然科学基金-重金属Tb作用于植物细胞膜的微观化学行为研究(BK2009401)(2009-2012);

(2)江苏省工业支撑计划项目-聚氨酯无机仿生表面构建的关键技术及生物医用研究(BE2009164)(2009-2012);

(3)国家自然科学基金项目-稀土作用于辣根细胞膜的若干生物无机化学行为研究(20971069)(2010-2012);

(4)“211工程”三期建设项目-特异生物功能化合物的分子设计(20090211)(2009-2013)。

(5)中央财政支持地方高校发展专项资金项目(2010~2013)。

【科研成果及奖励】

作为项目主持人近三年来, 完成中美合作项目、国家自然科学基金、国家发改委、江苏省高技术及教育部重点项目等8项、在研项目3项。

在J.Biol.Inorg.Chem., J.Phys.Chem., Dalton Transactions, Ecotoxicology and Environmental Safety, Annals of Botany,Electrochimica Acta., J. Electro. Chem.,J. Mater. Chem.等学术期刊上合作发表SCI论文60余篇(其中第一及通信作者42篇)。被国外SCI期刊如Journal of Physical Chemistry(B、C), Dalton Transactions, International Journal of Biological Sciences, Biological Trace Element Research, Langmuir, Ecotoxicology and Environmental Safety, Annals of Botany, Environmental Chemistry Letters等他引223次,单篇最高引用17次。

2007年应邀在 “13th International Conference on Biological Inorganic Chemistry(ICBIC13,维也纳)”会上报告;2009年又收到“ICBIC14,日本”会议报告的邀请。

【所获专利】

获得1项美国专利及6项中国(授权)发明专利。其中,一项特色研究成果用于出口经济作物,05-07连续三年该产品获得欧盟生态证书及出口美国、加拿大、丹麦、德国等国家和地区,净增经济效益96万美元。

【在读硕、博士人数】

 

【已毕业硕、博士人数】

 

【指导本科生人数】

 

【以上资料更新日期】